Talk:5α-Reductase 2 deficiency

This is the talk page for discussing improvements to the 5α-Reductase 2 deficiency article.
This is not a forum for general discussion of the article's subject.

Put new text under old text. Click here to start a new topic.
New to Wikipedia? Welcome! Learn to edit; get help.

Article policies

Find medical sources: Source guidelines · PubMed · Cochrane · DOAJ · Gale · OpenMD · ScienceDirect · Springer · Trip · Wiley · TWL

Archives: 1, 2: 12 months

The contentious topics procedure applies to this page. This page is related to gender-related disputes or controversies or people associated with them, which has been designated as a contentious topic.

Editors who repeatedly or seriously fail to adhere to the purpose of Wikipedia, any expected standards of behaviour, or any normal editorial process may be blocked or restricted by an administrator. Editors are advised to familiarise themselves with the contentious topics procedures before editing this page.

Medicine Mid‑importance

	Medicine portal This article is within the scope of WikiProject Medicine, which recommends that medicine-related articles follow the Manual of Style for medicine-related articles and that biomedical information in any article use high-quality medical sources. Please visit the project page for details or ask questions at Wikipedia talk:WikiProject Medicine.MedicineWikipedia:WikiProject MedicineTemplate:WikiProject Medicinemedicine
Mid	This article has been rated as Mid-importance on the project's importance scale.

Molecular Biology: Genetics

	This article is within the scope of WikiProject Molecular Biology, a collaborative effort to improve the coverage of Molecular Biology on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.Molecular BiologyWikipedia:WikiProject Molecular BiologyTemplate:WikiProject Molecular BiologyMolecular Biology
???	This article has not yet received a rating on the importance scale.
	This article is supported by the Genetics task force (assessed as Low-importance).

Ideal sources for Wikipedia's health content are defined in the guideline Wikipedia:Identifying reliable sources (medicine) and are typically review articles. Here are links to possibly useful sources of information about 5α-Reductase 2 deficiency.

PubMed provides review articles from the past five years (limit to free review articles)
The TRIP database provides clinical publications about evidence-based medicine.
Other potential sources include: Centre for Reviews and Dissemination and CDC

New Chapter Layout?

It's easy to just edit, but maybe we can discuss on the layout of chapters in this wiki. For instance, we can combine Gender, 5-ARD in non-western culture and In popular culture to a major chapter "social interactions" or "social characteristics" or something like that. I think it can improve efficiency for reading the page. Chbse

2 redirects

Redirect from "Guevedoche" should really be "Guevedoce" - the former is either a misspelling or is quite rare.

I'd like to propose as well adding a redirect from "Penis-At-12"/"Penis-At-Twelve" - which is a common translation and often-used title for this phenomenon.

5-AR type I deficiency?

Does 5-AR type I deficiency also cause genitals to not develop normally? Or is only 5-AR type II responsible for penis growtH?

"DHT insensitivity syndrome" listed at Redirects for discussion

The redirect DHT insensitivity syndrome has been listed at redirects for discussion to determine whether its use and function meets the redirect guidelines. Readers of this page are welcome to comment on this redirect at Wikipedia:Redirects for discussion/Log/2023 August 30 § DHT insensitivity syndrome until a consensus is reached. (t · c) buidhe 14:00, 30 August 2023 (UTC)[reply]

Individuals or males

As someone who has never heard of this condition before, can someone explain why the Hell people keep suddenly changing "individuals" to "males" lately? Tarlby ^{(t) (c)} 14:10, 29 March 2025 (UTC)[reply]

Because it only affects genetic males. Hope this helps Equivamp - talk 14:12, 29 March 2025 (UTC)[reply]

I'm aware, but it's not like being an "individual" and "male" are mutually exclusive, so it feels like a huge waste of time for them. Is this just a transphobic thing going on or what? Tarlby ^{(t) (c)} 14:17, 29 March 2025 (UTC)[reply]

I can't speak for other editors (of which I was unaware until you created this section), but for myself, no. And I don't appreciate the aspersion. Equivamp - talk 14:20, 29 March 2025 (UTC)[reply]

Apologies. There are 3 random IPs without any context changing individuals to males with some transphobic vibes imo. And when I say that, I mean they change every single use of "individual" to male. You only changed the first mention for clarification which makes perfect sense and was good. Tarlby ^{(t) (c)} 14:27, 29 March 2025 (UTC)[reply]

The following sentence was added to the article lead in January 2022: [1] The condition is rare, only affects genetic males, and has a broad spectrum of presentations most apparent in the genitalia. Since then, some form of the term "genetic male" has been present in the intro.

In March, this language was changed by Tinm to read: [2] This deficiency causes atypical sex development in individuals that have an XY caryotype. [sic]

A previous RFC on this page found consensus that it is appropriate to frame the article in terms of genetic males -vs- phenotypical (or similar language) males. Removing all uses of the term "genetic male" from the article would seem to go against this previous consensus. I have therefore restored language similar to January 2022 to the intro.

As a nitpick, I also don't think it is completely accurate to use "individuals with an XY karotype" as a replacement for "genetic males". Individuals with conditions like XXY syndrome, XYY syndrome, and XXXY syndrome are also considered "genetic males", but they do not have the 46,XY karyotype. Based on my understanding of 5-ARD, there is nothing that would theoretically prevent people with XXY, XYY, XXXY from having this condition as well - although I'm not aware of any case studies demonstrating this. Astaire (talk) 17:22, 2 April 2025 (UTC)[reply]